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Antigenic Specificity | ULK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ULK1 Polyclonal Antibody detects endogenous levels of ULK1 protein. Two related serine/threonine kinases, UNC-51-like kinase 1 and 2 (ULK1, ULK2), were discovered as mammalian homologs of the C.elegans gene UNC-51 in which mutants exhibited abnormal axonal extension and growth. Both proteins are widely expressed and contain an amino-terminal kinase domain followed by a central proline/serine rich domain and a highly conserved carboxy-terminal domain. The roles of ULK1 and ULK2 in axon growth have been linked to studies showing that the kinases are localized to neuronal growth cones and are involved in endocytosis of critical growth factors, such as NGF. Yeast two-hybrid studies found ULK1/2 associated with modulators of the end |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human ULK1 |
Other Names | [Rabbit ULK1; ULK1; KIAA0722; Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; hATG1; Unc-51-like kinase 1] |
Gene, Accession # | [ULK1], Gene ID: 8408, NCBI: NP_003556, UniProt: O75385 |
Catalog # | MBS9707347 |
Price | $130, $220, $325 |
Order / More Info | ULK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |