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Antigenic Specificity | TRRAP (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TRRAP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3015-3049 amino acids from the C-terminal region of human TRRAP. Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a vir |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Transformation/transcription domain-associated protein; 350/400 kDa PCAF-associated factor; PAF350/400; STAF40; Tra1 homolog; TRRAP; PAF400] |
Gene, Accession # | [TRRAP], Gene ID: 8295, NCBI: NP_001231509.1, UniProt: Q9Y4A5 |
Catalog # | MBS9215621 |
Price | $165, $370 |
Order / More Info | TRRAP (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | McMahon S.B.,et al.Cell 94:363-374(1998).Vassilev A.,et al.Mol. Cell 2:869-875(1998).Hillier L.W.,et al.Nature 424:157-164(2003).Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Scherer S.W.,et al.Science 300:767-772(2003). |