RRAGA/B Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | RRAGA/B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total RRAGA/B protein. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.Schuermann A., J. Biol. Chem. 270:28982-28988(1995).Li Y., J. Virol. 71:1576-1582(1997).Hirose E., J. Cell Sci. 111:11-21(1998). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human RRAGA/B. |
| Other Names | [Ras-related GTP-binding protein A; Rag A; RagA; Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1] |
| Gene, Accession # | [RRAGA/B], Gene ID: 10670, NCBI: NP_006561.1, UniProt: Q7L523 |
| Catalog # | MBS9401612 |
| Price | $200, $255 |
| Order / More Info | RRAGA/B Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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