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Antigenic Specificity | IRS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Insulin receptor substrate 1(IRS1) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Insulin receptor substrate 1(IRS-1) is a signalling adapter protein that in humans is encoded by the IRS-1 gene. It is mapped to 2q36.3. This gene exhibited no intrinsic enzyme activity, and it can serve as a docking protein involved in binding and activating other signal transduction molecules after being phosphorylated on tyrosine by insulin receptor kinase. IRS1 plays a key role in transmitting signals from the insulin and insulin-like growth factor-1(IGF-1) receptors to intracellular pathways PI3K/Akt and Erk MAP kinase pathways. IRS1 also has important biological function for both metabolic |
Immunogen | Immunogen: E.coli-derived human IRS1 recombinant protein (Position: S1041-Q1242). Human IRS1 shares 78% and 80% amino acid (aa) sequences identity with mouse and rat IRS1, respectively. |
Other Names | [HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS 1; IRS-1; IRS1; IRS1_HUMAN; OTTHUMP00000164234; insulin receptor substrate 1], [IRS1; IRS1; HIRS-1; IRS-1] |
Gene, Accession # | [IRS1], Gene ID: 3667, NCBI: NP_005535.1, UniProt: P35568 |
Catalog # | MBS177448 |
Price | $315 |
Order / More Info | IRS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |