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Antigenic Specificity | PIK3CG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Links G-protein coupled receptor activation to PIP3 production. Involved in immune, inflammatory and allergic responses. Modulates leukocyte chemotaxis to inflammatory sites and in response to chemoattractant agents. May control leukocyte polarization and migration by regulating the spatial accumulation of PIP3 and by regulating the organization of F-actin formation |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human PIK3CG (NP 002640.2). |
Other Names | [PI3K; PIK3; PI3CG; PI3Kgamma; p110gamma; p120-PI3K] |
Gene, Accession # | [PIK3CG], Gene ID: 5294, NCBI: NP_002640.2, UniProt: P48736 |
Catalog # | MBS8543988 |
Price | $280 |
Order / More Info | PIK3CG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |