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Antigenic Specificity | Mouse Il27 (Center), 124-150 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Il27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-150 amino acids from the Central region of mouse Il27. Cytokine with pro-and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma producti |
Immunogen | n/a |
Other Names | [Interleukin-27 subunit alpha; IL-27 subunit alpha; IL-27-A; IL27-A; p28; Il27; Il27a] |
Gene, Accession # | [Il27], Gene ID: 246779, NCBI: NP_663611.1, UniProt: Q8K3I6 |
Catalog # | MBS9203319 |
Price | $165, $370 |
Order / More Info | Mouse Il27 (Center), 124-150 Antibody from MYBIOSOURCE INC. |
Product Specific References | Li, J.J., et al. J. Immunol. 185(7):4401-4409(2010) Zhang, J., et al. J. Biol. Chem. 285(28):21269-21281(2010) Baker, B.J., et al. Glia 58(9):1082-1093(2010) Murugaiyan, G., et al. Proc. Natl. Acad. Sci. U.S.A. 107(25):11495-11500(2010) Zhu, S., et al. J. Immunol. 184(5):2348-2354(2010) |