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Antigenic Specificity | CD3E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of Jurkat cell lines, using CD3E antibody. Immunofluorescence analysis of U2OS cell using CD3E antibody. Blue: DAPI for nuclear staining. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery (1). This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: 3, ug and '. Each of these polypeptides contains at least one immunoreceptor tyrosine-based activation motif (ITAM) (2). Engagement of TCR complex with foreign antigens induces tyrosine phosphoryla |
Immunogen | Immunogen: Recombinant protein of human CD3E |
Other Names | n/a |
Gene, Accession # | [CD3E] |
Catalog # | MBS419800 |
Price | $385 |
Order / More Info | CD3E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |