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Antigenic Specificity | MADCA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MADCA protein. MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases associated with MADCAM1 include Colitis and Inflammatory Bowel Disease. Among its related pathways are Paxillin-dependent events mediated by a4b1 and Cell adhesion molecules (CAMs). The protein encoded by MADCAM1 is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different |
Immunogen | Immunogen: Synthesized peptide derived from part region of human MADCA protein at amino acid sequence of 260-340 |
Other Names | [Rabbit MADCA; Mucosal addressin cell adhesion molecule 1; MAdCAM-1; hMAdCAM-1] |
Gene, Accession # | [MADCA], Gene ID: 8174, NCBI: NP_570116.2, UniProt: Q13477 |
Catalog # | MBS9709739 |
Price | $130, $220, $325 |
Order / More Info | MADCA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |