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Antigenic Specificity | Caspase-1(P20) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Caspase-1(CASP1) detection. Tested with WB, IHC-P in Human. Background: Caspase 1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, IL18, and IL33 precursor proteins. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue. The Caspase1 gene consists of 10 exons spanning at least 10.6 kb. The Caspase 1 gene is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas, by Southern DNA blot analysis of rodent-human hybrids and by in situ hybridization to normal human metaphase chrom |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CASP1 (135-152aa CSLEEAQRIWKQKSAEIY). |
Other Names | [Caspase-1(CASP-1); caspase 1, apoptosis-related cysteine peptidase; CASP 1; CASP-1; CASP1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase-1 subunit p20; Caspase1; ICE; IL 1 beta converting enzyme; IL 1BC; IL-1 beta-converting enzyme; IL-1BC; IL1 beta converting enzyme; IL1B convertase; IL1BC; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; Interleukin 1B converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; P45], [CASP1; CASP1; ICE; P45; IL1BC; IL1BC; IL1BCE; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme] |
Gene, Accession # | [CASP1], Gene ID: 834, NCBI: P29466.1, UniProt: P29466 |
Catalog # | MBS175225 |
Price | $315 |
Order / More Info | Caspase-1(P20) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |