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Antigenic Specificity | TOM70 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TOM70 Antibody: The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. TOM70, an important member of the TOM complex, contains a tetratricopeptide repeat domain similar to those found in cytosolic chaperones such as Hsp90 and Hsc70 and provides a docking site for these proteins. This interaction is thought to be a critical first step in the TOM70-dependent mitochondrial import, followed by contact between the preprotein and TOM70. After targeting to TOM70, preproteins are translocated through the outer membrane via the TOM40 import pore complex. The precise mechanism of how preproteins progress from TOM70 to TOM40 |
Immunogen | Immunogen: TOM70 antibody was raised against a 15 amino acid synthetic peptide near the center of human TOM70. Buffer: TOM70 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TOM70; KIAA0719; TOM70; Mitochondrial import receptor subunit TOM70; Mitochondrial precursor proteins import receptor; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)], [TOMM70A; TOMM70A; KIAA0719; TOM70] |
Gene, Accession # | [TOMM70A], Gene ID: 9868, NCBI: NP_055635, UniProt: O94826 |
Catalog # | MBS150544 |
Price | $375 |
Order / More Info | TOM70 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |