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Antigenic Specificity | F4-80 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1 -3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1 -3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria |
Immunogen | Immunogen: A synthetic peptide of human F4-80 Calculated Molecular Weight: 102kDa |
Other Names | [Emr1; DD7A5-7; EGF-TM7; F4/80; Gpf480; Ly71; TM7LN3], [Emr1; Emr1; Ly71; F4/80; Gpf480; TM7LN3; DD7A5-7; EGF-TM7; Gpf480] |
Gene, Accession # | [EMR1], Gene ID: 13733, NCBI: Q61549.1, UniProt: Q61549 |
Catalog # | MBS127209 |
Price | $200, $275, $430 |
Order / More Info | F4-80 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |