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Antigenic Specificity | SRGAP1 (Center), 469-497 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SRGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-497 amino acids from the Central region of human SRGAP1. GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. |
Immunogen | n/a |
Other Names | [SLIT-ROBO Rho GTPase-activating protein 1; srGAP1; Rho GTPase-activating protein 13; SRGAP1; ARHGAP13; KIAA1304] |
Gene, Accession # | [SRGAP1], Gene ID: 57522, NCBI: NP_065813.1, UniProt: Q7Z6B7 |
Catalog # | MBS9209470 |
Price | $165, $370 |
Order / More Info | SRGAP1 (Center), 469-497 Antibody from MYBIOSOURCE INC. |
Product Specific References | Davila, S., et al. Genes Immun. 11(3):232-238(2010) Voss, M., et al. BMC Immunol. 10, 53 (2009) : Olsen, J.V., et al. Cell 127(3):635-648(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006) Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005) |