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Antigenic Specificity | Human CD49b |
Clone | [16B4] |
Host Species | Mouse |
Reactive Species | human; does not react with:rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Flow Cytometry, Immunohistology - Frozen,Paraffin (1), ELISA, Immunoprecipitation, Western Blotting, Immunofluorescence,Functional Assays (2) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD49b antibody, clone 16B4 recognizes human CD49b, also known as integrin alpha2, collagen receptor, Platelet membrane glycoprotein Ia or VLA-2 subunit alpha. CD49b is a 1181 amino acid ~160kDa single pass type-1 transmembrane glycoprotein posessing multiple FG-GAP repeats and a single VWFA domain. Mouse anti human CD49b antibody, clone 16B4 is identified as capable of immunoprecipitating a non-reducible alpha subunit from I125 surface labelled Human cell line extract. It is confirmed as specific to the alpha 2 subunit by relative expression of antigen on various cell lines by FACS, and its recognition of affinity purified alpha 2 beta 1 in dot blots. |
Immunogen | Immunogen: Purified human beta 1 preparation from HT1080 fibrosarcoma cell extract. Perservative Stabilisers: 0.09% Sodium Azide. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. Fusion Partners: Spleen cells from immunized BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line |
Other Names | [INTEFRIN ALPHA 2 CHAIN, VLA-2], [ITGA2; ITGA2; BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; CD49B; GPIa] |
Gene, Accession # | [CD49b], Gene ID: 3673, NCBI: NP_002194.2, UniProt: P17301 |
Catalog # | MBS215438 |
Price | $175 |
Order / More Info | Human CD49b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |