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Antigenic Specificity | Glutamine Synthetase |
Clone | [GS-6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | unconjugated |
Size | 5 Control Slides, 0.1 mL (Concentrate), 3 ml (Prediluted) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamine synthetase (GS) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. GS is present predominantly in the brain, kidneys, and liver. GS in the brain participates in the metabolic regulation of glutamate, the detoxification of brain ammonia, the assimilation of ammonia, recyclization of neurotransmitters, and termination of neurotransmitter signals. In normal liver, GS expression is seen in pericentral hepatocytes, but not in mid-zonal or periportal hepatocytes. GS positive tumor cells are believed to be derived from GS positive hepatocytes. GS immunoreactivity has been seen in a majority of hepatocellular carcinoma (HCC), including cases of |
Immunogen | Immunogen: Human Glutamine Synthetase aa. 1-373. |
Other Names | [glutamine synthetase; Glutamine synthetase; glutamine synthetase; glutamate-ammonia ligase; Glutamate decarboxylase (EC:4.1.1.15); Glutamate--ammonia ligase], [GLUL; GLUL; GS; GLNS; PIG43; PIG59; GLNS; GS] |
Gene, Accession # | Gene ID: 2752, NCBI: NP_001028228.1 |
Catalog # | MBS370304 |
Price | $130, $205, $240 |
Order / More Info | Glutamine Synthetase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |