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Antigenic Specificity | RASIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RASIP1 antibody detects endogenous levels of total RASIP1. Function: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.Subunit St |
Immunogen | Immunogen: A synthesized peptide derived from human RASIP1 Subcellular Location: Golgi Apparatus Tissue Specificity: Highly expressed in heart. Detected at lower levels in placenta and pancreas. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (92%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [FLJ20401; Rain; RAIN protein fragment; RAIN_HUMAN; Ras interacting protein 1; Ras-interacting protein 1; RASIP 1; RASIP1; RASIP1 protein] |
Gene, Accession # | [RASIP1], Gene ID: 54922, NCBI: NP_060275.2, UniProt: Q5U651 |
Catalog # | MBS9610126 |
Price | $240, $280 |
Order / More Info | RASIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |