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Antigenic Specificity | CASP9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using CASP9 antibody. Immunofluorescence analysis of A549 cell using CASP9 antibody. Blue: DAPI for nuclear staining. Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family (1, 2). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response (3-6). Cleaved caspase-9 further processes other caspase members, including caspa |
Immunogen | Immunogen: Recombinant protein of human CASP9 |
Other Names | [caspase-9 isoform beta; Caspase-9; caspase-9; caspase 9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3] |
Gene, Accession # | [CASP9], Gene ID: 842, NCBI: NP_001264983.1, UniProt: P55211 |
Catalog # | MBS4150142 |
Price | $385 |
Order / More Info | CASP9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |