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Antigenic Specificity | Zika Virus Envelope (EIII Domain) (ZIKV E Protein) |
Clone | [ZKA64] |
Host Species | Human |
Reactive Species | n/a |
Isotype | IgG1,k |
Format | purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes and binds specifically to the EDIII domain of the Zika Virus envelope protein (ZIKV E). It does not cross-react with Dengue virus envelope protein (DENV E). The main route of Zika Virus (ZIKV) infection is through bites by Aedes mosquitos, but the virus may also be sexually and vertically transmitted. Although most of the ZIKV infections are asymptomatic or cause only mild symptoms, there is evidence that ZIKV infection can lead to neurological complications, such as Guillain-Barre syndrome in adults and congenital birth defects, including microcephaly in the developing fetus, likely through its ability to infect human neural progenitor cells. Whereas flavivirus envelope (E) proteins mediate fusion and are the main target of neut |
Immunogen | Immunogen: EBV-immortalized memory B cells derived from ZIKV-infected, DENV-naive human donors. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS6120626 |
Price | $610 |
Order / More Info | Zika Virus Envelope (EIII Domain) (ZIKV E Protein) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection: K. Stettler, et al.; Science 353, 823 (2016). |