CASPASE-7 (C-TERMINAL) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CASPASE-7 (C-TERMINAL) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Immunohistology Paraffin*, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises an epitope within the C-terminal region (CT) of Caspase-7, a 35kDa cysteine protease, otherwise known as ICE-like Apoptotic Protease 3 (ICE-LAP3). . . Caspase-7, a member of the ICE/Ced-3 subfamily, is an executioner caspase which undergoes proteolytic cleavage of its precursor to form active p12 and p20 subunits. Evidence that activation of Caspase-7 occurs during cell death induced by the cytokine death receptors Fas/APO-1 and the receptor of tumour necrosis factor (TNFR-1), coupled with the fact that granzyme-B activated Caspase-7 cleaves the nuclear enzyme poly (ADP-ribose) polymerase (PARP), suggests an important role for Caspase-7 in both cytokine-mediated and Granzyme-B mediated apoptosis pathways. MBS221847 re |
| Immunogen | Immunogen: A 16 amino acid peptide from human Caspase-7 carboxy-terminus Histology Positive Control Tissue: Skeletal muscle tissue Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human Caspase-7 (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
| Other Names | [caspase-7 isoform alpha; Caspase-7; caspase-7; ICE-like apoptotic protease 3; apoptotic protease MCH-3; caspase 7, apoptosis-related cysteine protease; caspase 7, apoptosis-related cysteine peptidase; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3], [CASP7; CASP7; MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3; MCH3; CASP-7; ICE-LAP3] |
| Gene, Accession # | Gene ID: 840, NCBI: NP_001218.1, UniProt: P55210 |
| Catalog # | MBS221847 |
| Price | $375 |
| Order / More Info | CASPASE-7 (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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