Phospho-Histone H2AX (S139) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Histone H2AX (S139) |
| Clone | monoclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | IgG |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
| Immunogen | Immunogen: A synthesized peptide |
| Other Names | [Histone H2AX; H2a/x; Histone H2A.X; H2AFX; Histone H2AX] |
| Gene, Accession # | [H2AX], Gene ID: 3014, NCBI: NP_002096.1, UniProt: P16104 |
| Catalog # | MBS7110764 |
| Price | $185, $265 |
| Order / More Info | Phospho-Histone H2AX (S139) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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