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Antigenic Specificity | Mouse CD80, PE |
Clone | [RMMP-1] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.05 mg, 0.3 mg |
Concentration | 0.1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD80 (B7-1, B7/BB1) (Mouse CD80 (B7-1)). MBS520456 reacts with the murine CD80 (B7-1) molecule. This member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constituitively expressed on dendritic cells, monocytes, and peritoneal macrophages; and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours. Applications include: flow cytome |
Immunogen | n/a |
Other Names | [CD80, PE (Clone RMMP-1) (rat IgG2a); PE Mouse CD80], [CD80; B7-1] |
Gene, Accession # | [CD80], Gene ID: 397161, NCBI: AAL58443.1 |
Catalog # | MBS520456 |
Price | $450, $1920 |
Order / More Info | Mouse CD80, PE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |