Human Bcl-2 homologous antagonist/killer Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Bcl-2 homologous antagonist/killer |
| Clone | [PAT8B4AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2a k |
| Format | Protein G purified |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: BAK1 is a member of the BCL2 protein family. The BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators which are involved in a wide variety of cellular activities. The BAK1 gene encodes a receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtamembrane domain, and a kinase domain. BAK1 localizes to mitochondria, and functions to induce apoptosis. BAK1 interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to a loss in membrane potential and the release of cytochrome c. Furthermore, BAK1 interacts with the tumor suppressor P53 after exposure to cell stress. BAK1 expression is |
| Immunogen | Immunogen: Anti-human BAK1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BAK1 amino acids 29-187 purified from E Coli. |
| Other Names | [BAK1; Bcl-2 homologous antagonist/killer, Mouse Human; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7; BAK1; BAK; BCL2L7; CDN1; MGC3887; BAK-LIKE; MGC117255], [BAK1; BAK1; BAK; CDN1; BCL2L7; BAK-LIKE; BAK; BCL2L7; CDN1; Bcl2-L-7] |
| Gene, Accession # | [BAK1], Gene ID: 578, NCBI: NP_001179.1 |
| Catalog # | MBS140355 |
| Price | $140, $205, $505 |
| Order / More Info | Human Bcl-2 homologous antagonist/killer Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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