Edit |   |
---|---|
Antigenic Specificity | Mouse Protein S100-A8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly |
Immunogen | Immunogen: Recombinant mouse Protein S100-A8 protein(1-93aa) |
Other Names | [Calgranulin-A; Chemotactic cytokine CP-10; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; Pro-inflammatory S100 cytokine; S100 calcium-binding protein A8; Caga; Mrp8; S100a8], [S100a8; S100a8; p8; B8Ag; CFAg; Caga; MRP8; CP-10; 60B8Ag; AI323541; Caga; Mrp8; MRP-8; p8] |
Gene, Accession # | [S100-A8], Gene ID: 20201, NCBI: NP_038678.1, UniProt: P27005 |
Catalog # | MBS1494146 |
Price | $160, $235 |
Order / More Info | Mouse Protein S100-A8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |