Rig-I Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Rig-I antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Rig-I |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Antiviral innate immunity depends on the combination of parallel pathways triggered by virus detecting proteins in the Toll-like receptor (TLR) family and RNA helicases, such as Rig-I (retinoic acid-inducible gene I) and MDA-5 (melanoma differentiation-associated antigen 5), which promote the transcription of type I interferons (IFN) and antiviral enzymes (1-3). TLRs and helicase proteins contain sites that recognize the molecular patterns of different virus types, including DNA, single-stranded RNA (ssRNA), double-stranded RNA (dsRNA), and glycoproteins. These antiviral proteins are found in different cell compartments; TLRs (i.e. TLR3, TLR7, TLR8, and TLR9) are expressed on endosomal membranes and helicases are localized to the cytoplasm. |
| Immunogen | Immunogen: A synthetic peptide of human DDX58 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [DDX58; DKFZp434J1111; DKFZp686N19181; FLJ13599; RIG-I] |
| Gene, Accession # | [Rig-I], Gene ID: 23586, NCBI: NP_055129.2, UniProt: O95786 |
| Catalog # | MBS8503700 |
| Price | $310 |
| Order / More Info | Rig-I Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Yoneyama, M. and Fujita, T. (2007) J Biol Chem 282, 15315-8. 2. Meylan, E. and Tschopp, J. (2006) Mol Cell 22, 561-9. 3. Thompson, A.J. and Locarnini, S.A. (2007) Immunol Cell Biol 85, 435-45. 4. Imaizumi, T. et al. (2002) Biochem Biophys Res Commun 292, 274-9. 5. Zhang, X. et al. (2000) Microb Pathog 28, 267-78. 6. Yoneyama, M. et al. (2005) J Immunol 175, 2851-8. 7. Yoneyama, M. et al. (2004) Nat Immunol 5, 730-7. 8. Hornung, V. et al. (2006) Science 314, 994-7. 9. Pichlmair, A. et al. (2006) Science 314, 997-1001. 10. Kato, H. et al. (2006) Nature 441, 101-5. 11. Childs, K. et al. (2007) Virology 359, 190-200. 12. Meylan, E. et al. (2005) Nature 437, 1167-72. 13. Xu, L.G. et al. (2005) Mol Cell 19, 727-40. 14. Kawai, T. et al. (2005) Nat Immunol 6, 981-8. 15. Seth, R.B. et al. (2005) Cell 122, 669-82. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies