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Antigenic Specificity | Sortilin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Sortilin Antibody detects endogenous levels of Sortilin. Description: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the fo |
Immunogen | Immunogen: A synthesized peptide derived from human Sortilin. Tissue Specificity: Expressed in brain and prostate (at protein level). Expressed at high levels in brain, spinal cord, heart, skeletal muscle, thyroid, placenta and testis. Expressed at lower levels in lymphoid organs, kidney, colon and liver. |
Other Names | [100 kDa NT receptor; Glycoprotein 95; Gp 95; Gp95; LDLCQ6; Neurotensin receptor 3; NT 3; NT3; NTR 3; NTR3; OTTHUMP00000013784; SORT 1; SORT_HUMAN; SORT1 (gene name); Sort1; Sortilin 1; Sortilin] |
Gene, Accession # | [SORT1], Gene ID: 6272, NCBI: Q99523.3, UniProt: Q99523 |
Catalog # | MBS9611497 |
Price | $240, $280 |
Order / More Info | Sortilin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |