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Antigenic Specificity | Phospho-L-plastin (Tyr300) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-L-plastin (Tyr300) Antibody detects endogenous levels of L-plastin only when phosphorylated at Tyr300. Description: Actin-binding protein (PubMed:16636079, PubMed:17294403, PubMed:28493397). Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Modulates the cell surface expression of IL2RA/CD25 and CD69 (PubMed:17294403).Post Translational Modifications: Phosphorylated on a serine residue in response to costimulation through TCR/CD3 and CD2 or CD28. Serine phosphorylation promotes association with the actin cytoskeleton and targeting to peripheral cell projections.Subunit Structure: Monomer. Interacts with AIF1 (By similarity). Interact |
Immunogen | Immunogen: A synthesized peptide derived from human L-plastin around the phosphorylation site of Tyr300. Tissue Specificity: Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T-lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells. |
Other Names | [CP64; L plastin; L-plastin; Larval cuticle protein 1; LC64P; LCP-1; LCP1; Lplastin; Lymphocyte cytosolic protein 1; Plastin 2; Plastin-2; PLS2; PLSL_HUMAN] |
Gene, Accession # | [LPL], Gene ID: 3936, NCBI: EAX08758.1, UniProt: P13796 |
Catalog # | MBS9610586 |
Price | $225, $280, $340 |
Order / More Info | Phospho-L-plastin (Tyr300) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |