Edit |   |
Antigenic Specificity | CD1a/HTA1 (Mature Langerhans Cells Marker) |
Clone | [C1A/1506R] |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic l |
Immunogen | Immunogen: Recombinant full-length human CD1a protein Cellular Localization: Cell Surface |
Other Names | [Cortical thymocyte antigen CD1A; Epidermal dendritic cell marker CD1a; FCB6; HTA1; T cell surface antigen T6 / Leu 6; T-Cell Surface Glycoprotein CD1A] |
Gene, Accession # | [CD1A], Gene ID: 909, NCBI: NP_001307581.1, UniProt: P06126 |
Catalog # | MBS4380303 |
Price | $190, $340, $340 |
Order / More Info | CD1a/HTA1 (Mature Langerhans Cells Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Cassaday, RD.et al.2007. Clin. Cancer Res. 13: 540-549. Matsuda, A.et al.2009. Invest. Ophthalmol. Vis. Sci. 50: 2871-2877. Gulubova, M.et al.2008. Clin. Exp. Metastasis. 25: 777-785. McNally, AK.et al.2011. Exp. Mol. Pathol. 91: 673-681. |