Phospho-MEK2 (Thr394) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-MEK2 (Thr394) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunoprecipitation (IP), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-MEK2 (Thr394) antibody detects endogenous levels of MEK2 only when phosphorylated at Threonine 394. Description: MEK2 a dual-specificity protein kinase of the STE7 kinase family. Phosphorylated and activated by Raf and Mos kinases. Phosphorylates a Thr and a Tyr residue in a Thr-Glu-Tyr sequence located in the activation loop of ERK2 and ERK3.Function: Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).Subunit Structure: Interacts with MORG1 (By similarity). Interacts with SGK1 (PubMed:19447520). Interacts with KSR1 (PubMed:10409742).Post-translational Modifications: MAPKK is |
| Immunogen | Immunogen: A synthesized peptide derived from human MEK2 around the phosphorylation site of Threonine 394 Subcellular Location: Cytoplasm, Cytoskeleton, Microtubule Organizing Center, Centrosome. Cytoplasm, Cytoskeleton, Microtubule Organizing Center, Spindle Pole Body. Cytoplasm. Nucleus. Localizes at centrosomes during prometaphase, midzone during anaphase and midbody during telophase/cytokinesis. Predicted Cross Reactivity: Bovine, Sheep, Dog, Chicken Similarity: Bovine (91%), Sheep (91%), Do |
| Other Names | [Cardiofaciocutaneous syndrome; CFC syndrome; CFC4; Dual specificity mitogen activated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; FLJ26075; MAP kinase kinase 2; map2k2; MAPK/ERK kinase 2; MAPK/ERK kinase 2; MAPKK 2; MAPKK2; MEK 2; MEK2; Microtubule associated protein kinase kinase 2; Mitogen activated protein kinase kinase 2; Mitogen activated protein kinase kinase 2 p45; MKK 2; MKK2; MP2K2_HUMAN; OTTHUMP00000165826; OTTHUMP00000165827; PRKMK 2; PRKMK2] |
| Gene, Accession # | [MEK2], Gene ID: 5605, NCBI: NP_109587.1, UniProt: P36507 |
| Catalog # | MBS9601053 |
| Price | $240, $280 |
| Order / More Info | Phospho-MEK2 (Thr394) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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