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Antigenic Specificity | SMG6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER). |
Immunogen | Immunogen: Recombinant human Telomerase-binding protein EST1A protein |
Other Names | [Telomerase-binding protein EST1A; EST1-like protein A; Ever shorter telomeres 1A; Smg-6 homolog; Telomerase subunit EST1A; hSmg5/7a; SMG6; C17orf31; EST1A; KIAA0732] |
Gene, Accession # | [SMG6], Gene ID: 23293, NCBI: NP_001243756.1, UniProt: Q86US8 |
Catalog # | MBS7001005 |
Price | $160, $235 |
Order / More Info | SMG6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |