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Antigenic Specificity | GABA (B) R2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GABA (gamma-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system and plays a crucial role in the modulation of neuronal activity.1, 2 The GABA transmitter interacts with three types of receptors: the ionotropic receptors, GABA (A)R and GABA (C)R, and the metabotropic GABA (B) receptor, [GABA (B)R].3 The latter belongs to the G-protein-coupled receptor (GPCR) superfamily and mediates slow synaptic inhibition in the brain and spinal cord1, 4. The functional GABA (B) receptor [GABA (B)R] is a heterodimer consisting of two subunits, the GABA (B)R1 and the GABA (B)R2. These subunits were demonstrated to have complementary roles essential for the functional receptor.5, 6 GABA (B)R2 has been shown to be essenti |
Immunogen | Immunogen: Peptide CKDPIEDINSPEHIQRRLSL corresponding to residues 875-894 of human GABA (B)R2 (Accession number O75899). |
Other Names | [GABA (B)] |
Gene, Accession # | n/a |
Catalog # | MBS4157633 |
Price | $725 |
Order / More Info | GABA (B) R2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |