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Antigenic Specificity | MCP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MCP protein. The protein encoded by CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by CD46 may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript var |
Immunogen | Immunogen: Synthesized peptide derived from part region of human MCP protein at amino acid sequence of 10-90 |
Other Names | [Rabbit MCP; Membrane cofactor protein; TLX; Trophoblast leukocyte common antigen; CD46] |
Gene, Accession # | [MCP], Gene ID: 4179, NCBI: P15529.3, UniProt: P15529 |
Catalog # | MBS9709797 |
Price | $130, $220, $325 |
Order / More Info | MCP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |