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Antigenic Specificity | Human CD11c |
Clone | [3.9] |
Host Species | n/a |
Reactive Species | n/a |
Isotype | IgG1 |
Format | Protein A purified |
Size | 120 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human CD11c (alpha X integrin) complexes with CD18 (beta 2 integrin) to form the complement receptor type 4 (CR4) heterodimer which binds to fibrinogen and is involved with monocyte/granulocyte adhesion during inflammatory responses (2). CD11c expression is restricted to leukocytes mainly of myeloid lineage with highest expression on macrophages. |
Immunogen | Immunogen: Human rheumatoid synovial fluid cells/monocytes. Buffer: 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
Other Names | [CD11cAllophycocyanin; human CD11c/APC*; Integrin alpha X], [CR4; p150] |
Gene, Accession # | [CD11c] |
Catalog # | MBS666887 |
Price | $405 |
Order / More Info | Human CD11c Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. N. Hogg, et al, (1986) Eur J Immunol 16: 240-248. 2. S.A. Stacker & T.A. Springer, (1991) J Immunol 146: 648-655. 3. M. Patarroyo, (1994) Immunobiology 191: 474-477. 4. Leukocyte Typing V (1995) (S.F. Schlossman, et al., eds.) Oxford University Press, Oxford,p. 1590-1592. 5. Yoshino N, Honda M, et al. (2000) Exp Anim 49(2):97-110. |