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Antigenic Specificity | GFRA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of GFRA2 protein. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by GFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. GFRA2 is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for GF |
Immunogen | Immunogen: Synthesized peptide derived from part region of human GFRA2 protein at amino acid sequence of 320-400 |
Other Names | [Rabbit GFRA2; GDNF receptor beta; GDNFR-beta; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; RET ligand 2; TGF-beta-related neurotrophic factor receptor 2] |
Gene, Accession # | [GFRA2], Gene ID: 2675, NCBI: O00451.2, UniProt: O00451 |
Catalog # | MBS9709209 |
Price | $130, $220, $325 |
Order / More Info | GFRA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |