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Antigenic Specificity | TLR2 |
Clone | [BV31-9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.03 mL, 0.1 mL |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types are regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulate TLR2, whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes. |
Immunogen | Immunogen: Recombinant human TLR2 |
Other Names | [Toll-like receptor 2; TLR2; TLR2; CD282; TIL4], [TLR2; TLR2; TIL4; CD282; TIL4] |
Gene, Accession # | [TLR2], Gene ID: 7097, NCBI: NP_003255.2, UniProt: O60603 |
Catalog # | MBS840028 |
Price | $150, $345 |
Order / More Info | TLR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |