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Antigenic Specificity | Chk1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Chk1 is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. |
Immunogen | Immunogen: Chk1 antibody was raised in Rabbit using the peptide sequence around aa 315~319 (S-S-S-Q-P) derived from Human Chk1 as the immunogen. |
Other Names | [Rabbit Chk1; Chk1; Chk1; Chk-1; Chk 1; Ab 317; Chk1; Chk-1; Chk 1; CHEK1] |
Gene, Accession # | [Chk1], Gene ID: 1111, NCBI: AAC51736.1 |
Catalog # | MBS5309714 |
Price | $295 |
Order / More Info | Chk1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |