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Antigenic Specificity | MLL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MLL2 protein. KMT2D (Lysine Methyltransferase 2D) is a Protein Coding gene. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Chromatin organization. The protein encoded by KMT2D is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in KMT2D have been shown to be a cause of Kabuki syndrome. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human MLL2 protein at amino acid sequence of 1430-1510 |
Other Names | [Rabbit MLL2; Histone-lysine N-methyltransferase 2D; Lysine N-methyltransferase 2D; ALL1-related protein; Myeloid/lymphoid or mixed-lineage leukemia protein 2] |
Gene, Accession # | [MLL2], Gene ID: 8085, NCBI: NP_003473.3, UniProt: O14686 |
Catalog # | MBS9709846 |
Price | $130, $220, $325 |
Order / More Info | MLL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |