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Antigenic Specificity | IFITM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-media |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-50 on human Interferon-induced transmembrane protein 3. Conjugation: Unconjugated |
Other Names | [Affinity Purified Interferon-induced transmembrane protein 3; 1 8U; Fragilis; IFITM3; Interferon Induced Transmembrane Protein 3; Interferon inducible; Interferon inducible protein 1 8U; Interferon Inducible Protein 15; Interferon Inducible Protein Homolog; IP15] |
Gene, Accession # | [IFITM3], Gene ID: 10410, NCBI: AFF60350, UniProt: Q01628 |
Catalog # | MBS5400437 |
Price | $390 |
Order / More Info | IFITM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |