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Antigenic Specificity | VDAC1/Porin |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Voltage-dependent anion-selective channel 1 (VDAC-1) is a beta barrel protein that in humans is encoded by the VDAC1 gene. This protein is a voltage-dependent anion channel and shares high structural homology with the other VDAC isoforms (VDAC2 and VDAC3), which are involved in the regulation of cell metabolism, mitochondrial apoptosis, and spermatogenesis. Its Overexpression and misregulation could lead to apoptosis in the cell and a variety of diseases within the body. In particular, since VDAC1 is the major calcium ion transport channel, its dysfunction is implicated in cancer, Parkinson's (PD), and Alzheimer's disease. |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to VDAC1/Porin protein. |
Other Names | [VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; VDAC; Voltage-dependent anion-selective channel protein 1], [VDAC1; VDAC1; PORIN; VDAC-1; VDAC; VDAC-1; hVDAC1] |
Gene, Accession # | [VDAC1], Gene ID: 7416, NCBI: NP_003365.1, UniProt: P21796 |
Catalog # | MBS435284 |
Price | $350, $565 |
Order / More Info | VDAC1/Porin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |