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Antigenic Specificity | TTF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TTF1 antibody detects endogenous levels of total TTF1. Function: Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.Subunit Structure: Oligomer. The oligomeric structure enables to interact simultaneously with two separate DNA fragments. Interacts with BAZ2A/TIP5. Interacts with CAVIN1.Similarity: The N-terminal region (NRD) inhibits DNA-binding via its interaction with the C-terminal region. |
Immunogen | Immunogen: A synthesized peptide derived from human TTF1 Subcellular Location: Nucleus. Nucleus > Nucleolus. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (90%), Horse (90%), Sheep (90%), Rabbit (89%), Dog (90%) |
Other Names | [RNA polymerase I termination factor; Transcription termination factor 1; Transcription termination factor I; Transcription termination factor RNA polymerase I; TTF 1; TTF-1; TTF-I; Ttf1; TTF1_HUMAN] |
Gene, Accession # | [TTF1], Gene ID: 7270, NCBI: NP_001192225.1, UniProt: Q15361 |
Catalog # | MBS9609147 |
Price | $240, $280 |
Order / More Info | TTF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |