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Antigenic Specificity | HPV11 E6 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human papilloma viruses type 11 |
Isotype | n/a |
Format | unconjugated |
Size | 0.6 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects HPV11 E6 recombinant fusion proteins MBP-E6 and GFP-E6 expressed in transfected mammalian cells. Goat polyclonal antibody to HPV11 E6. E6 is one primary oncoprotein of high risk HPV types expressed early in the HPV life cycle. After the host cell is infected viral early promoter is activated and a polycistronic primary RNA containing all six early ORFs is transcribed. This polycistronic RNA then undergoes active RNA splicing to generate multiple isoforms of mRNAs. One of the spliced isoform RNAs, E6, serves as an E7 mRNA to translate E7 protein. HPV genome integrate into host genome by disruption of E2 ORF, preventing E2 repression on E6 and E7. Thus, viral genome integration into host DNA genome increases E6 expression. The E6 prot |
Immunogen | Immunogen: Purified recombinant peptide derived from within residues 65 aa to N-terminal of HPV11 E6 produced in E. coli. Antigen: Purified recombinant peptide derived from within residues 65 aa to N-terminal of HPV11 E6 produced in E. coli. |
Other Names | n/a |
Gene, Accession # | [HPV11 E6] |
Catalog # | MBS448009 |
Price | $285 |
Order / More Info | HPV11 E6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |