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Antigenic Specificity | TIMP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TIMP1 protein. Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.Anieta M. Sieuw |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TIMP1. |
Other Names | [tissue inhibitor of metalloproteinase 1] |
Gene, Accession # | [TIMP1], Gene ID: 7076, NCBI: NP_003245.1, UniProt: P01033 |
Catalog # | MBS9410104 |
Price | $200, $255 |
Order / More Info | TIMP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |