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Antigenic Specificity | AP2A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: Rabbit polyclonal AP2A1 (1) antibody was raised against a recombinate human AP2A1 protein 22-199aa (BC014214). |
Other Names | [AP2A1 protein; AP-2 complex subunit alpha-1; AP-2 complex subunit alpha-1; 100 kDa coated vesicle protein A; adapter-related protein complex 2 alpha-1 subunit; adapter-related protein complex 2 subunit alpha-1; adaptin, alpha A; adaptor protein complex AP-2 subunit alpha-1; adaptor-related protein complex 2 subunit alpha-1; alpha-adaptin A; alpha1-adaptin; clathrin assembly protein complex 2 alpha-A large chain; clathrin-associated/assembly/adaptor protein, large, alpha 1; plasma membrane adaptor HA2/AP2 adaptin alpha A subunit; adaptor-related protein complex 2, alpha 1 subunit; 100 kDa coated vesicle protein A; Adaptor protein complex AP-2 subunit alpha-1; Adaptor-related protein complex 2 subunit alpha-1; Alpha-adaptin A; Alpha1-adaptin; Clathrin assembly protein complex 2 alpha-A large chain; Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit], [AP2A1; AP2A1; ADTAA; CLAPA1; AP2-ALPHA] |
Gene, Accession # | [AP2A1], Gene ID: 160, NCBI: AAH14214.1 |
Catalog # | MBS416635 |
Price | $230 |
Order / More Info | AP2A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Sitaram,A., Piccirillo,R., Palmisano,I. et al. Localization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 function. Mol. Biol. Cell 20 (5), 1464-1477 (2009). |