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Antigenic Specificity | GNAT3 (Guanine Nucleotide-binding Protein G(t) Subunit alpha-3, Gustducin alpha-3 Chain) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | reacts with: humanpredicted: dog, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 0.5mg/ml |
Applications | ELISA (EL/EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human GNAT3. Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibod |
Immunogen | Immunogen: Synthetic peptide corresponding to C-KNQFLDLNLKKEDKE, from human GNAT3, at the internal region of the protein (NP 001095856.1). |
Other Names | [-GNAT3 (Guanine Nucleotide-binding Protein G(t) Subunit alpha-3, Gustducin alpha-3 Chain)] |
Gene, Accession # | Gene ID: 346562, NCBI: NP_001095856.1, UniProt: A8MTJ3 |
Catalog # | MBS6005782 |
Price | $570 |
Order / More Info | GNAT3 (Guanine Nucleotide-binding Protein G(t) Subunit alpha-3, Gustducin alpha-3 Chain) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |