Edit |   |
---|---|
Antigenic Specificity | Cathepsin D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cathepsin D Polyclonal Antibody detects endogenous levels of Cathepsin D protein. CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Cathepsin D |
Other Names | [Rabbit Cathepsin D; CPSD; Cathepsin D] |
Gene, Accession # | [CTSD], Gene ID: 1509, NCBI: NP_001900.1, UniProt: P07339 |
Catalog # | MBS9704542 |
Price | $130, $220, $325 |
Order / More Info | Cathepsin D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |