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Antigenic Specificity | FGR |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FGR antibody detects endogenous levels of total FGR. Description: FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Ba |
Immunogen | Immunogen: Purified recombinant fragment of human FGR expressed in E. Coli Subcellular Location: Cell Membrane. Cell Membrane. Cell Projection > Ruffle Membrane. Cytoplasm > Cytosol. Cytoplasm > Cytoskeleton. Mitochondrion Inner Membrane. Mitochondrion Intermembrane Space. Detected in mitochondrial intermembrane space and at inner membranes (By similarity). Colocalizes with actin fibers at membrane ruffles. Detected at plasma membrane lipid rafts. Tissue Specificity: Detected in neutrophils, mon |
Other Names | [c fgr; c fgr protooncogene; c src 2 proto oncogene; c src2; Fgr; FGR_HUMAN; FLJ43153; Gardner Rasheed feline sarcoma viral (v fgr); Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; p55 c fgr protein; P55 FGR; P55-FGR; p55c fgr; p58-Fgr; p58c fgr; p58c-Fgr; Proto oncogene c Fgr; Proto oncogene tyrosine protein kinase FGR; Proto-oncogene c-Fgr; SRC 2; SRC2; Tyrosine protein kinase Fgr; Tyrosine-protein kinase Fgr] |
Gene, Accession # | [FGR], Gene ID: 2268, NCBI: NP_001036194.1, UniProt: P09769 |
Catalog # | MBS9602430 |
Price | $235, $295, $370 |
Order / More Info | FGR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |