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Antigenic Specificity | ARHGEF11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ARHGEF11 antibody detects endogenous levels of total ARHGEF11. Function: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.Subunit Structure: Interacts with GNA12 and GNA13 through the RGS domain. Interacts with RHOA, PLXNB1 and PLXNB2. Interacts with SLC1A6 (By similarity). Interacts (via DH domain) with GCSAM (via C-terminus).Post-translational Modifications: Phosphorylated by MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14). Ubiquitinated by the BCR(KLHL20) E3 ubiq |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Membrane. Translocated to the membrane upon stimulation. Tissue Specificity: Ubiquitously expressed. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Horse (100%), Sheep (83%), Rabbit (100%), Dog (92%) |
Other Names | [ARHGB_HUMAN; ARHGEF 11; ARHGEF11; DKFZp667F1223; Glutamate transporter EAAT4 associated protein 48; GTRAP 48; GTRAP48; KIAA0380; OTTHUMP00000038716; OTTHUMP00000038717; PDZ RHOGEF; PDZ-RhoGEF; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; Rho guanine nucleotide exchange factor 11; RhoA specific guanine nucleotide exchange factor; RhoGEF glutamate transport modulator] |
Gene, Accession # | [ARHGEF11], Gene ID: 9826, NCBI: NP_055599.1, UniProt: O15085 |
Catalog # | MBS9605885 |
Price | $240, $280 |
Order / More Info | ARHGEF11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |