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Antigenic Specificity | LC3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents (1,2). Autophagy is generally activated by conditions of nutrient deprivation, but it has also been associated with a number of physiological processes including development, differentiation, neurodegenerative diseases, infection, and cancer (3). Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3) (4) and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy (5). Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy (6-9). Cleavage of LC3 at the carboxy t |
Immunogen | Immunogen: A synthetic peptide of human LC3 Calculated Molecular Weight: 15kDa |
Other Names | [LC3B: LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3; MAP1LC3B], [MAP1LC3B; MAP1LC3B; LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3; MAP1ALC3; MAP1A/MAP1B LC3 B] |
Gene, Accession # | [MAP1LC3B], Gene ID: 81631, NCBI: Q9GZQ8.3, UniProt: Q9GZQ8 |
Catalog # | MBS126887 |
Price | $275, $430 |
Order / More Info | LC3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |