SOX2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SOX2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SOX2 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of SOX2. SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. Sox2, Oct-4 and Nanog co-operate in this network, and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. |
| Immunogen | n/a |
| Other Names | [transcription factor SOX-2; Transcription factor SOX-2; transcription factor SOX-2; SRY-box 2], [SOX2; SOX2; ANOP3; MCOPS3] |
| Gene, Accession # | [SOX2], Gene ID: 6657, NCBI: NP_003097.1, UniProt: P48431 |
| Catalog # | MBS857011 |
| Price | $280 |
| Order / More Info | SOX2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Mutations in SOX2 cause anophthalmia.Fantes J., Ragge N.K., Lynch S.-A., McGill N.I., Collin J.R.O., Howard-Peebles P.N., Hayward C., Vivian A.J., Williamson K., van Heyningen V., FitzPatrick D.R.Nat. Genet. 33:461-463(2003). 2. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S.Cell 131:861-872(2007). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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