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Antigenic Specificity | TLR3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, thromugh MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 805 of mouse TLR3 |
Other Names | n/a |
Gene, Accession # | [TLR3], NCBI: AKL79824.1 |
Catalog # | MBS840335 |
Price | $150, $290 |
Order / More Info | TLR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |