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Antigenic Specificity | Rat CD152 |
Clone | [WKH 203] |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 0.1 mg, 0.5 mg |
Concentration | 0.1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rat CD152. anti-rat CD152 monoclonal antibody is specific for the cytotoxic T lymphocyte-associated protein 4 (CTLA-4), also called CD152. This antigen is known to be the receptor for B7 ligands (CD80 and CD86) present on antigen presenting cells. A subset of CD4 T cells expressing CD25 and CTLA-4 has been recognized as a potent suppressor cell population, counteracting autoimmunity and inflammation. These 'regulatory' T cells (Treg) which produce the anti-inflammatory cytokine interleukin-10 (IL-10) but not IL-2, are able to suppress the proliferation of costimulated CD25- negative indicator cells. The capacity of these naturally occurring regulatory T cells to suppress autoimmunity and inflammation suggests that therapies whi |
Immunogen | Immunogen: Purified rCTLA-4hlg fusion protein. Donor: BALB/c mice spleen cells. Fusion Partner: X63 Ag8.653 myeloma cells |
Other Names | n/a |
Gene, Accession # | [CD152] |
Catalog # | MBS520057 |
Price | $250, $420 |
Order / More Info | Rat CD152 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |