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Antigenic Specificity | NGF-Receptor (p75)/CD271 (Soft Tissue Tumor Marker) |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts. |
Immunogen | Immunogen: Recombinant human p75 NGFR protein fragment (around aa 281-421) (exact sequence is proprietary) |
Other Names | [CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Nerve growth factor receptor (NGFR); p75 ICD; p75 Neurotrophin receptor; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16)] |
Gene, Accession # | [NGFR], Gene ID: 4804, NCBI: NP_002498.1, UniProt: P08138 |
Catalog # | MBS4381113 |
Price | $190, $340, $340 |
Order / More Info | NGF-Receptor (p75)/CD271 (Soft Tissue Tumor Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Wang, W., et al. 2009. Eur. J. Surg. Oncol. 35: 826-832. 2. Soland, T.M., et al. 2008. Histopathology 53: 62-72. |